https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Ampullary cancers harbor ELF3 tumor suppressor gene mutations and exhibit frequent WNT dysregulation https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:24864 Wed 11 Apr 2018 12:41:17 AEST ]]> Targeting mTOR dependency in pancreatic cancer https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20668 Wed 11 Apr 2018 09:35:51 AEST ]]> Clinical and pathologic features of familial pancreatic cancer https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18742 2 years) was associated with poor survival in both groups.Conclusions: FPC represents 9% of PC, and the risk of malignancy in kindred does not appear to be confined to the pancreas. Patients with FPC have more precursor lesions and include fewer active smokers, but other clinicopathologic factors and outcome are similar to those in patients with SPC. Furthermore, some FPC kindreds may exhibit anticipation. A better understanding of the clinical features of PC will facilitate efforts to uncover novel susceptibility genes and the development of early detection strategies.]]> Sat 24 Mar 2018 08:02:49 AEDT ]]>